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The quassia tree grows from 50 to 100 feet high; it has smooth, gray bark and alternate, odd-pinnate leaves with oblong, pointed leaflets. Its small flowers are yellowish or greenish, its fruit is a small rupe about the size of a pea.

Quassin extract is said to by many times more bitter than quinine, and is used as an ingredient in many medications that would normally contain quinine. Like quinine it is a febrifuge and is used by the traditional healers of Brazil for malaria, fevers, as a bitter digestive aid, an insecticide, and for liver and gallbladder problems among other conditions.

Quassia is indigenous to Brazil, Peru, Venezuela, Suriname, Colombia, Argentina, and Guyana where it is used extensively for fevers. The herb is extremely bitter, the name amargo means "bitter" in Spanish. The general name, Quassia, comes from a man named Quassi of Surinam who had incredible success using it as a secret ingredient for a particularly bad fever that was running rampant through Surinam.

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Precautions - Quassia should not be used during pregnancy. Quassia has been documented to have an antifertility effect in studies and men undergoing fertility treatment or those wishing to have children should avoid using this herb.Large amounts of Quassia can irritate the mucous membrane of the stomach leading to nausea and vomiting.