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St. John's wort is probably the first herb used for mild-to-moderate depression. St. John's wort also has antibacterial and antiviral properties and, because of its anti-inflammatory properties, has been used to help with wounds and burns. The American College of Physicians-American Society of Internal Medicine (ACP-ASIM) released guidelines for antidepressant herbs which state that St. John's wort may be effective against mild depression, at least in the short term. The ACP-ASIM team that studied the research found that across 14 trials, 62% of depression patients given St. John's wort reported improved symptoms compared with 38% taking an inactive placebo.
In recent years, there has been renewed interest in St. John's wort with regard to depression and there has been a great deal of scientific research on this topic. St. John's wort is one of the most commonly purchased herbal products in the United States.
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Parts Used
The dried flowering tops and leaf.
Typical Preparations
Traditionally used as a tea, sometimes available in tea bags; also used to make a red St. John's oil for use in liniments and lotions, but only from fresh material. May also be administered as a capsule or extract for convenience.
Precautions
St. John's wort extracts may increase sensitivity to sunlight and risk of sunburn, but this is extremely rare when the whole herb is used.
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