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Three species of the genus Rhamnus (the name derived from the Greek rhamnos, a branch) are possessed of the same medicinal properties in varying degrees. The Common or Purging Buckthorn, a much-branched shrub, usually about 6 feet high, but sometimes as much as 10 or 12 feet, is indigenous to North Africa, the greater part of Europe and North Asia. Though found throughout England in woods and thickets and near brooks, it is practically confined to a calcareous soil, except in a few counties, such as Bucks., Herts., Oxon. and Wilts. In Scotland it occurs only in a single locality.

Cascara sagrada is used as a laxative. Cascara Sagrada, known as sacred bark, is one of earth's most popular herbal products. Its popularity is no accident. As a nutritional support for the eliminative function, the bark has been used by cultures around the world, including the Native North Americans and American settlers. Spanish missionaries noticed its use among the natives and called it sacred; hence, the Spanish name. It was first marketed in 1877, and was later acknowledged and used by the medical profession.

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Dose - The usual dose ranges from 20 mg to 70 mg daily of the anthraquinones. Products containing cascara sagrada should not be used for more than eight or ten days.

Special Precautions - Fresh bark can cause nausea and vomiting. The bark should be stored for at least a year or undergo heat processing to eliminate this problem. Pregnant women and nursing mothers should avoid cascara sagrada. People with intestinal blockage, undiagnosed stomach pain, or symptoms that might indicate appendicitis must avoid laxatives such as cascara sagrada. People with diarrhea, inflammatory bowel disease, or intestinal ulcers must not use cascara sagrada. Children younger than twelve with constipation should not be treated with cascara sagrada.